Can Beauty be Found in a Bottle? New Study Shows it Can

CLINICAL TRIAL SHOWS BIOCELL COLLAGEN II REDUCES WRINKLES AND IMPROVES HYDRATION

June 23, 2011, Newport Beach CA — BioCell Technology LLC announces the completion of the first human skin study of BioCell Collagen II® in women who have undergone natural and UV‐intensified aging processes. In broad brushstrokes, this study has demonstrated the safety and significant efficacy of BioCell Collagen II® in improving a variety of aging‐associated facial effects measured both qualitatively and quantitatively.

BioCell Collagen II® is a naturally‐occurring matrix containing hydrolyzed collagen and highly‐bioavailable hyaluronic acid. It had been strongly implicated as a healthy‐aging ingredient that promotes both joint and skin health, and specifically causing the “beauty from the inside” effects that have traditionally been achieved with external or invasive wrinkle‐reducing treatments. The outcome of previous studies demonstrated an excellent safety profile and efficacy in bioavailability, increased levels of hyaluronic acid, and inhibition of hyaluronidase, providing more turgid, hydrated, and supple skin. BioCell Collagen II® has also been shown in human clinical trials to reduce joint discomfort and stiffness as much as 40% in eight weeks.

Encouraged by the consistently favorable outcome of the earlier studies, BioCell Technology recently completed a study investigating the effects of BioCell Collagen II® on diverse parameters relevant to aged appearance of the facial skin. These parameters included dryness, wrinkles, deep lines and collagen content. This study on skin aging has proven that BioCell Collagen II® is indeed an essential "nutricosmetic" ingredient that promotes healthy aging. Its multi‐layered mechanisms of action have been shown to synergistically antagonize the skin aging process and promote younger‐looking appearance with better hydration, higher collagen content, reduced wrinkle counts and shallower line depth. As a result, a majority of the study participants experienced a remarkable improvement in skin texture, together with hydration, reduced scaling, and improved blood microcirculation.

Dr. Joosang Park, principal investigator of the research team, says that the details of the study will be published in the near future. Dr. Park who conducted research at Harvard Medical School for many years applies the rigorous standards of pharmaceutical research and practices to nutritional ingredients. "The extraordinary fact about this study is that the subjects took BioCell Collagen II® orally for skin beauty;” said Dr. Park, “this was not a topical study. It means that BioCell Collagen II® is not only a true nutraceutical, but that it can offer less wrinkles, increased collagen, and supple, hydrated skin by working from the inside‐out.” Dr. Park also stated, “This and earlier studies demonstrate that BioCell Collagen II can support the skin dermis collagen network containing collagen types I and III as well as collagen type II in the joint. I’m encouraged about these findings and that it adds to the portfolio of research that makes BioCell Collagen II® a true nutricosmetic substantiated by multiple human studies.”

Ms. Asma Ishaq, vice president of marketing and Dr. Park will present the top‐line data and discuss the research at the upcoming Nutricosmetic Summit 2011 in Las Vegas. The conference focuses on the emerging and rapidly growing nutricosmetic segment of the dietary supplement industry, which is a direct result of a growing acceptance of younger people investing in anti‐aging measures and more so by 11,000 baby boomers turning 50 every day. This trend will continue for the next 10 years, and by 2012, 50 percent of the entire US population will be over 50.

Leading this category with science, BioCell Technology also earns praise from industry experts. “It’s important to see new science emerging in this area, specifically with ingested products, and we applaud companies such as BioCell that are leading this charge”, notes Len Monheit, Executive Director of the New Hope Supply Network and hosts of the Nutricosmetic Summit. “Moreover, we are glad that the Summit is the place where this advance is to be presented, and the commitment that BioCell has made in working with our Supply Network to validate and build this category globally.”

About BioCell Collagen II:

BioCell Collagen II® is an innovative dietary ingredient marketed as a healthy aging nutritional supplement that promotes both healthy joints and more youthful‐looking skin. It is unique in that it is a naturally‐occurring matrix whose three major constituents, collagen type II, chondroitin sulfate, and hyaluronic acid, are reduced to highly‐bioavailable, very low molecular weight forms due to its patented hydrolysis process. Made exclusively from articular sternum cartilage, its composition is similar to that of human articular joint cartilage.

About BioCell Technology:

Founded in 1997, BioCell Technology, LLC is the exclusive supplier of BioCell Collagen II® and owns the exclusive rights to market it under US Patents. The product logo is registered and is available for display on the labels of BioCell Technology, LLC's private label clients for marketing under their own brand names or formulas. For more information on BioCell Collagen II, please contact BioCell Technology, LLC at (714) 632‐1231 or visit www.biocelltechnology.com.